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DRUG INTERACTIONS with Norvir (ritonavir) 4/10/96

The following list was compiled and distributed by Abbott Labs.
(Note: if your browser is unable to view browsers, please view the list file.)

Norvir should NOT be coadministered with:
Potential alternatives (may not be therapeutically equivalent):
drug class generic name brand name
generic name brand name # patients
analgesic meperidine
piroxicam
propoxyphene
Demoral
Feldene
Darvon

acetaminophen
aspirin
oxycodone
Tylenol

Percodan
n=135
n=43
n=23
cardiovascular
(antiarrhythmic)
amiodarone
encainide
flecainide
propafenone
quinidine
Cordarone
Enkaid
Tambocor
Rythmol

- very limited clinical experience-
anti-mycobacterial rifabutin Mycobutin
clarithromycin
ethambutol
Biaxin
Myambutol
n=156
n=66
cardiovascular
(calcium channel blocker)
bepridil Vascor
-very limited clinical experience-
cold & allergy
(antihistimine)
astemizole
terfenadine
Hismanal
Seldane

loratadine Claritin n=36
gastrointestinal cisapride Propulsid
-very limited clinical experience-
psychotropic
(antidepressant)
bupropion Wellbutrin
fluoxetine
desipramine
Prozac
Nopramin
n=28
psychotropic
(neuroleptic)
clozapine Clozaril
-very limited clinical experience-
psychotropic
(sedative/hypnotic)
aplrazolam
clorazepate
diazepam
estazolam
flurazepam
midazolam
triazolam
zolpidem
Xanax
Tranxene
Valium
Prosom
Dalmane
Versed
Halcion
Ambien

temazepam
lorazepam
Restonil
Ativan
n=60
n=33

DO NOT CO-ADMINISTER antabuse with Norvir. Ritonavir contains alcohol, which can produce reactions when coadministered with disulfiram (antabuse) or other drugs that produce disulfiram-like reactions (e.g., metronidazole).

see the PRECAUTIONS-DRUG INTERACTIONS and the DRUG-DRUG INTERACTIONS sections of the Norvir package insert for more information about actual and potential effects on drugs coadministered with Norvir; this package insert is available at your pharmacy.

The following statements are quoted from the Abbott package insert. Please, refer to the insert for elaboration of the subjects.

See also, Letter from Abbott sent to doctors.

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Last modified 8/20/96
copyright 1996 natap