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  After decreases in reported new AIDS cases every year from 1995 through 2000, from 2000 to 2001, the CDC reported AIDS cases went up 8% in the USA. The declines were 12%, 20%, and 13% in years 1996, 1997, and 1999. These were shortly after the advent of HAART and protease inhibitors. Without knowing of any official explanations, perhaps the overall benefit waned as adherence and drug resistance emerged.
The changes in new AIDS cases were reported by geographic region of the US. Perhaps most alarming is the large increase in the Mid-Atlantic Region, which includes New York State, New Jersey, and Pennsylvania. after declines in the rate of newly reported AIDS cases of 13%, 7%, and 28% in the years 1997-1998, 1998-1999, and 1999-2000, from 2000-2001 the increase was 34%. Also increasing were rates in South Atlantic Region: DC, FLA., GA, MD, S Car, W VA, and VA (14%).
In the New England region (Conn, Maine, Mass, VT, New Hampshire, Rhode Island) , after increases in rates in 1998-1999 of 27%, the rates declines in the last two years: 11% from '99-00 and 22% from 2000-2000.
In the Region including Indiana, Illinois, Michigan, Ohio, and Wisconsin, the rate declined 18% from 2000 to 2001. This followed declines in 1996 (16%), 1997 (22%), and 1998 (3%) and an increase in 1999-2000 of 13%. After declines in 3 of the 4 previous years in 2000 to 2001 the rate increased 14%.
In the Alabama, KY, Miss, and Tenn Region, the rate declined 8.5% in 2000 to 2001 period.
In Ark, LA, Okl, and Texas region the rate increased 9% after 4 straight years of declining rates.
In the Mountain Region (AZ, Col, Idaho, Montana, Utah, Wyo, Nevada, New Mex), there was no change from 2000 to 2001.
In the Pacific Region which includes California, Puerto Rico, Virgin Islands, and additional Far Western States, the rates declined each of the last several years including the most recent period.
In the Region including Iowa, Kansas, Minnesota, Missouri, Nebraska, North Dakota and South Dakota, rates have declined the last two years (12% and 4.7%).
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