Back grey_arrow_rt.gif
 
 
Tests for H.I.V. Reach a Record
 
 
  NY Times Published: December 1, 2010
 
The number of American adults tested for H.I.V., the virus that causes AIDS, reached a record high in 2009, the Centers for Disease Control and Prevention said Tuesday.
 
Nonetheless, about 55 percent of all adults - and about 28 percent of all people who are at higher risk for getting infected - have still never been tested.
 
Starting in 2006, the disease centers began urging doctors to order H.I.V. tests as part of routine blood work for all patients. Success has been modest; the percentage of all adults who have ever had a test rose only to 45 percent after years of holding steady at 40 percent.
 
Almost one-third of people who learn they are infected find out only when they fall seriously ill, the disease centers said, meaning they have presumably infected others during that time and have also missed the opportunity to get treatment.
 
----------------
 
CDC: HIV Testing Policy Pays Off - CDC Report Below
 
"For adults, CDC recommends routine HIV screening in health-care settings.....Trends in HIV testing show that the percentage of persons ever tested for HIV remained stable at approximately 40% from 2001 to 2006, increasing to 45.0% in 2009, representing 82.9 million persons.....in 2009, 82.9 million adults aged 18--64 years reported having ever been tested for HIV, an increase of 11.4 million since 2006. However, 55% of adults have never been tested for HIV. Young persons (aged 18--24 years) had rates of HIV diagnoses that were similar to other age groups, but their testing rates were lower. In addition, although late diagnoses of HIV declined by 5% from 2001 to 2007 in the 33 states with mature HIV reporting systems, approximately one third of persons diagnosed with HIV infection in 2007 in 37 states were diagnosed late. These results indicate that progress has been made, but continued and intensified efforts are needed to identify persons with undiagnosed infection......approximately 60% of blacks or African Americans have been tested for HIV at least once in their lives, a higher percentage than any other racial/ethnic group. Despite the higher percentage of persons who report ever having been tested, the disproportionately high rates of diagnoses among blacks or African Americans (112.1 per 100,000) and Hispanics or Latinos (40.5 per 100,000), suggest that adults from these subpopulations might benefit from more frequent testing to facilitate early diagnosis. The burden of HIV is greatest among gay, bisexual, and other men who have sex with men (MSM), who comprised more than half of all diagnoses in 2008. Surveys have found that a high percentage (58%) of MSM report testing in the preceding 12 months. However, 45% of HIV-infected MSM who were unaware of their infection reported having an HIV test in the preceding 12 months, indicating that they might have acquired their infection recently (15). Taken together, these findings indicate that although progress has been made towards increased testing rates among populations at risk, testing has not occurred at sufficient scale or repeated with enough frequency to identify all those with HIV.......CDC supports and provides resources for various activities that promote HIV testing and linkage to care and prevention services. In 2009, CDC granted $513 million to state and local health departments and community-based and other organizations for domestic HIV prevention and surveillance activities, including testing. The expanded testing initiative, a 3-year effort that began in 2007, was designed to increase testing, early diagnosis of HIV infection, and linkage to care and prevention services primarily among blacks or African Americans. It resulted in approximately 1.4 million persons being tested and 10,000 HIV infections identified. However, approximately 25% of those infected were not linked to care initially, and efforts are needed to ensure all diagnosed persons are linked to care. In 2010, CDC awarded additional funding for an expanded HIV testing initiative. The 2010 funding is being used to expand this initiative to reach more populations at risk, namely MSM, injection drug users, and Hispanics or Latinos
 
MedPage Today
Published: November 30, 2010
 
The CDC's 2006 recommendation that most adults and teens be screened for HIV infection appears to have paid off -- significantly more Americans have been tested for the virus since then -- but many more have yet to be screened, according to the agency.
 
An estimated 83 million people in the U.S. have been tested at least once as of 2009, according to National Health Interview Survey (NHIS) data -- an increase of more than 11 million from 2006, said CDC Director Thomas Frieden, MD, MPH.
 
But in a telephone briefing for reporters, he also pointed out that this figure represents only about 45% of the population for which testing is recommended. Moreover, Frieden said, "28% of high-risk adults have never been tested."
 
Details were published online in Morbidity and Mortality Weekly Report.
 
From 2001 to 2006, the percentage of Americans who had been tested had remained steady at about 40%, the NHIS data indicated.
 
In 2006, the CDC recommended that adolescents and most adults should be tested for HIV whenever they come into contact with the healthcare system, unless they specifically opt out.
 
"Today's data show that, following those recommendations, there was a significant increase in the number of Americans who were tested for the first time for HIV," Frieden said during the briefing.
 
"Because more people were tested, fewer people were diagnosed late with HIV," he added. Late diagnosis is defined as cases progressing to AIDS within a year of a positive test result.
 
According to the MMWR report, the percentage of HIV infections diagnosed late in 33 states with good-quality reporting systems was 32.3% in 2007 -- a decline of about 5% from its peak in 2004.
 
"These results indicate that progress has been made, but continued and intensified efforts are needed to identify persons with undiagnosed infection," the MMWR article stated.
 
"There are still 200,000 or more Americans who have HIV and don't know it," said Frieden. He added that the agency was looking for additional ways to further boost testing rates, especially among high-risk individuals.
 
Jonathan Mermin, MD, MPH, director of the CDC's HIV/AIDS Prevention Program, noted during the briefing that many high-risk individuals who have been tested "are not getting tested often enough."
 
He said that early detection is important from a cost perspective as well as for public and individual health.
 
Although early diagnosis increases the expense associated with the individual's care -- by increasing the number of years that a patient receives drugs and other therapies -- it cuts costs overall because it reduces the likelihood that the patient will infect other people, Mermin said.
 
One study found that undiagnosed HIV-infected individuals were 3.5 times as likely to transmit the virus as those who knew they were infected. Following a diagnosis, patients are more likely to take precautions against infecting others.
 
The average lifetime treatment cost of HIV infection is about $367,000, Mermin said.
 
--------------------------
 
LINK to Primary source: Morbidity and Mortality Weekly Report
Source reference:
 
Johnson A, et al "Vital Signs: HIV testing and diagnosis among adults -- United States, 2001-2009" MMWR 2010; 59(early release): 1-6.
 
CDC MMWR Report: Vital Signs: HIV Testing and Diagnosis Among Adults --- United States, 2001--2009
Early Release
November 30, 2010 / 59(Early Release);1-6
 
ABSTRACT

 
Background: Human immunodeficiency virus (HIV) infection is a major cause of morbidity, mortality, and health-care expenditures in the United States. HIV testing and linkage to care are essential to identify persons early in their course of infection to prevent progression to acquired immunodeficiency syndrome (AIDS) and death, and to reduce transmission.
 
Methods: CDC used 2001--2009 data from the National Health Interview Survey to estimate percentages of persons aged 18--64 years who reported ever being tested for HIV in the United States. Data from the National HIV Surveillance System were used to estimate numbers, percentages, and rates of HIV diagnoses, AIDS diagnoses, and late diagnoses of HIV infection (defined as an AIDS diagnosis made ≤12 months from an initial HIV diagnosis) for persons diagnosed with HIV infection during 2001--2008 and reported to CDC through June 2009; these were used to determine populations and regions most affected by HIV and AIDS, late diagnoses, and trends in late diagnoses over time.
 
Results: The percentage of persons aged 18--64 years ever tested for HIV was stable at approximately 40% from 2001 to 2006, increasing to 45.0% in 2009. The percentage of persons with late diagnoses of HIV infection was stable at approximately 37% from 2001 to 2004, decreasing to 32.3% by 2007 (most recent data available). In the 37 states with mature HIV reporting systems in 2007, the percentage of persons diagnosed late ranged from 25.0% to 47.2%. In 2008, most HIV diagnoses, by race/ethnicity, were among blacks or African Americans (51.2%) and, by transmission category, were among non--drug-injecting men reporting male-to-male sexual contact (55.0%). AIDS diagnosis rates were highest in the South and Northeast census regions and in the most populated states.
 
Conclusions: The number of persons in the United States who report ever being tested for HIV is increasing, and fewer persons are being diagnosed late in their infection. However, nearly one third of diagnoses still occur late. Increased testing efforts are needed, particularly among populations that account for most HIV diagnoses.
 
Implications for Public Health Practice: All health-care providers should expand routine HIV screening so that all adults are tested. Members of populations with higher rates of HIV diagnoses and living in geographic areas with high HIV prevalence should be screened more frequently than others. Persons likely to be at high risk for HIV infection (e.g., gay, bisexual, and other men who have sex with men) should be tested at least annually. Public health officials should emphasize the importance of HIV testing and allocate resources to increase testing among populations with the highest rates of HIV diagnoses.
 
Background
 
Human immunodeficiency virus (HIV) is a communicable infection that leads to a progressive disease with a long asymptomatic period. Approximately 56,000 persons in the United States are newly infected with HIV each year (1), which is nearly one new infection every nine and a half minutes. Without treatment, most persons develop acquired immunodeficiency syndrome (AIDS) within 10 years of HIV infection (2). Antiretroviral therapy delays this progression and increases the length of survival, but is most effective when initiated during the asymptomatic phase. It is estimated that on average, an HIV-positive person aged 25 years who receives high-quality care will survive an additional 39 years (3). CDC estimates that approximately 1.1 million adults and adolescents were living with HIV infection in the United States at the end of 2006; however, as many as one fifth (21%) were unaware of their infection (4,5). Persons with late diagnoses of HIV infection have missed opportunities for treatment during the asymptomatic period and for prevention of transmission to others; they also have a shortened life expectancy (6). Testing identifies infected persons, which enables them to seek medical care that can improve the quality and length of their lives and reduce risk for HIV transmission.
 
HIV testing and linkage to care are integral parts of a comprehensive strategy to identify all persons with HIV infections and to initiate early intervention. In 2010, the National HIV/AIDS Strategy established a goal of increasing, by 2015, from 79% to 90% the percentage of persons living with HIV who are aware of their infection (7). This report describes trends in HIV testing, rates of HIV and AIDS diagnoses, and trends in late diagnoses of HIV infection in the United States.
 
Methods
 
CDC used 2001--2009 data from the National Health Interview Survey (NHIS) to calculate the percentage of persons aged 18--64 years who reported ever being tested for HIV (excluding tests done for blood donations). NHIS is an ongoing, cross-sectional, household survey that provides data for a broad range of health measures based on in-person interviews with a nationally representative sample of the civilian noninstitutionalized population. Methods for this analysis have been described previously (8).
 
Estimates of numbers, percentages, and rates of HIV diagnoses, AIDS diagnoses, and trends in late diagnoses (defined as an AIDS diagnosis made ≤12 months from an initial HIV diagnosis) were used to determine populations and regions most affected by HIV and AIDS, late HIV diagnoses, and trends in late HIV diagnoses over time. These estimates were derived from data reported to the National HIV Surveillance System by 50 states and the District of Columbia (DC) for AIDS diagnoses and by states with long-term, confidential, name-based HIV reporting systems (33* since December 2000 and 37á since January 2005) for HIV diagnoses to allow for stabilization of data collection and adjustment of the data to monitor trends. Estimates presented are derived from cases that were followed up through December 2008 and reported through June 2009.
 
Results
 
In 2008, 44.6% of persons aged 18--64 years reported ever being tested for HIV (Table 1). The percentage of persons ever tested for HIV aged 18--24 years (33.9%) was lower than for persons aged 25--34 years (57.8%) and 35--44 years (56.7%), although rates of HIV diagnoses among persons in these age groups were similar (33.1, 37.6, and 38.0 per 100,000, respectively). The percentage of persons ever tested for HIV was higher among blacks or African Americans (61.8%) and Hispanics or Latinos (47.6%) than whites (40.9%). More than one quarter (28.3%)of persons who acknowledged having an HIV risk factorĄ had not been tested. Trends in HIV testing show that the percentage of persons ever tested for HIV remained stable at approximately 40% from 2001 to 2006, increasing to 45.0% in 2009, representing 82.9 million persons (Figure 1). Trends in late diagnoses also were stable at approximately 37% from 2001 to 2004, decreasing to 32.3% in 2007 among persons in 33 states. In 2007, the percentage of persons with HIV who had a late diagnosis was 32.3% for the 37 states combined; however, percentages of late diagnoses ranged from 25.0% to 47.2% among those states (Table 2). In 22 states, the percentage of persons with a late HIV diagnosis exceeded the percentage for the 37 states combined (32.3%). In these 22 states, percentages of late diagnoses ranged from 32.4% to 47.2%.
 
Nearly 40,000 adults were diagnosed with HIV infection in 2008 in the 37 states with mature HIV reporting systems (29.9 per 100,000) (Table 1). Men accounted for 75.0% of these diagnoses. Blacks or African Americans accounted for 51.2% of estimated diagnoses and had an HIV diagnosis rate (112.1 per 100,000) that was nine times the rate for whites (12.6 per 100,000). Hispanics or Latinos had an HIV diagnosis rate (40.5 per 100,000) approximately three times the rate for whites. By transmission category, men reporting male-to-male sexual contact accounted for the highest percentage (55.0%) of diagnoses, followed by heterosexual contact (31.8%), injection drug use (10.0%), and males reporting both male-to-male sexual contact and injection drug use (2.8%).
 
In 2008, among the 50 states and DC, AIDS diagnosis rates (per 100,000 population) for adults aged 18--64 years ranged from an estimated 2.0 per 100,000 in South Dakota to 130.1 per 100,000 in DC, with the highest rates occurring in the South and Northeast census regions and highly populated states (e.g., California and Illinois) (Figure 2).
 
Conclusions and Comment
 
In 2009, 82.9 million adults aged 18--64 years reported having ever been tested for HIV, an increase of 11.4 million since 2006. However, 55% of adults have never been tested for HIV. Young persons (aged 18--24 years) had rates of HIV diagnoses that were similar to other age groups, but their testing rates were lower. In addition, although late diagnoses of HIV declined by 5% from 2001 to 2007 in the 33 states with mature HIV reporting systems, approximately one third of persons diagnosed with HIV infection in 2007 in 37 states were diagnosed late. These results indicate that progress has been made, but continued and intensified efforts are needed to identify persons with undiagnosed infection. Trends in late HIV diagnoses and AIDS diagnoses can be used to monitor the progress of testing efforts for identifying infected persons. With increased testing and linkage to care, more persons infected with HIV are identified, and if persons are diagnosed early in their infection, earlier treatment will reduce disease progression to AIDS.
 
Identifying persons early in the course of infection saves lives, reduces morbidity and mortality, prevents new infections, and can reduce health-care expenditures. In one study, persons unaware of their infection were 3.5 times more likely to transmit HIV than persons aware of their infection (9). Persons who have been diagnosed can take precautions to avoid transmission and can be treated with appropriate antiretroviral therapy. Such therapy lowers the amount of virus in the blood and genital secretions, likely reducing the biologic risk for transmission (10,11). Every new HIV infection averted saves approximately $367,000 (2009 dollars) in lifetime medical costs (12). For all these reasons, HIV screening to identify infected persons and linking them to care and prevention services is a cornerstone of the national HIV prevention strategy (13).
 
For adults, CDC recommends routine HIV screening in health-care settings (14). CDC further recommends annual or more frequent testing of persons likely to be at high risk for HIV. Expanded efforts should be concentrated where the burden of disease is greatest. Knowledge of rates of AIDS diagnoses, HIV diagnoses, and HIV testing can be used to focus these efforts. For example, approximately 60% of blacks or African Americans have been tested for HIV at least once in their lives, a higher percentage than any other racial/ethnic group. Despite the higher percentage of persons who report ever having been tested, the disproportionately high rates of diagnoses among blacks or African Americans (112.1 per 100,000) and Hispanics or Latinos (40.5 per 100,000), suggest that adults from these subpopulations might benefit from more frequent testing to facilitate early diagnosis. The burden of HIV is greatest among gay, bisexual, and other men who have sex with men (MSM), who comprised more than half of all diagnoses in 2008. Surveys have found that a high percentage (58%) of MSM report testing in the preceding 12 months. However, 45% of HIV-infected MSM who were unaware of their infection reported having an HIV test in the preceding 12 months, indicating that they might have acquired their infection recently (15). Taken together, these findings indicate that although progress has been made towards increased testing rates among populations at risk, testing has not occurred at sufficient scale or repeated with enough frequency to identify all those with HIV.
 
The findings in this report are subject to at least four limitations. First, data from the NHIS sample of adults are self-reported and subject to recall bias and potential underreporting of sensitive information such as HIV testing and HIV risk factor status. Second, NHIS excludes active military personnel and those who live outside of households (e.g., persons who are incarcerated, in long-term care institutions, or homeless). Certain persons in these populations might be at greater risk for HIV infection than persons in households. Third, the NHIS sample does not include persons aged 13--17 years, who are included in CDC's 2006 HIV testing recommendations (14). Finally, national HIV surveillance with uniform reporting was not implemented fully until 2008. CDC regards data from states with confidential, name-based, HIV surveillance systems sufficient to monitor trends in HIV diagnoses after 4 years of reporting. The areas included in estimates of numbers and rates of diagnoses of HIV infection are based on the date of implementation of confidential name-based HIV infection reporting. Data from the 37 states account for approximately 68% of AIDS diagnoses in the 50 states and DC but might not be nationally representative. Data for the prevalence of AIDS diagnoses were used to provide an indication of the geographic distribution of HIV diagnoses because they are available for all states. However, AIDS diagnoses are a measure of late stage disease and do not accurately reflect the entire distribution of current HIV diagnoses.
 
CDC supports and provides resources for various activities that promote HIV testing and linkage to care and prevention services. In 2009, CDC granted $513 million to state and local health departments and community-based and other organizations for domestic HIV prevention and surveillance activities, including testing. The expanded testing initiative, a 3-year effort that began in 2007, was designed to increase testing, early diagnosis of HIV infection, and linkage to care and prevention services primarily among blacks or African Americans. It resulted in approximately 1.4 million persons being tested and 10,000 HIV infections identified. However, approximately 25% of those infected were not linked to care initially, and efforts are needed to ensure all diagnosed persons are linked to care. In 2010, CDC awarded additional funding for an expanded HIV testing initiative. The 2010 funding is being used to expand this initiative to reach more populations at risk, namely MSM, injection drug users, and Hispanics or Latinos. State and local health departments and health-care providers are essential to the implementation of these initiatives and integration of CDC's recommendations into practice. State and local laws and programs consistent with CDC's recommendations can facilitate increased HIV testing. Health-care providers should offer HIV screening for all persons who have never been tested for HIV infection, repeat testing for persons at increased risk for HIV, and referrals to risk reduction services (e.g., behavioral interventions) for at-risk persons testing HIV-negative. Similarly, persons who have never been tested for HIV should request an HIV test, and persons at increased risk for HIV should be tested at least annually (14).
 
The National HIV/AIDS Strategy provides an opportunity for refocusing and intensifying federal, state, and local HIV testing efforts (7). HIV testing and HIV surveillance data are essential to monitor and evaluate national, state, and local efforts against HIV and to set priorities for resource allocation. CDC remains committed to strengthening its efforts against the HIV epidemic and working with its partners to increase testing for all persons, promote periodic testing for persons at high risk, link persons to care, treatment, and prevention services, and ultimately reduce the burden of HIV in the United States.
 
Reported by
 
A Satcher Johnson, MPH, J Heitgerd, PhD, LJ Koenig, PhD, M VanHandel, MPH, BM Branson, MD, E Connelly, MP Aff, HI Hall, PhD, LA Valleroy, PhD, Div of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.
 
 
 
 
  icon paper stack View Older Articles   Back to Top   www.natap.org