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Effect of Statin Therapy on Reducing the Risk of Serious Non-AIDS-Defining Events and Non-Accidental Death in the AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) Cohort
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Reported by Jules Levin
CROI 2012 March 5-8 Seattle, WA
from Jules: Statin therapy was found in this ACTG study to provide a non-statistically significant benefit of up to 19% in a reduction to first non-AIDS events or death and a suggestion of benefit in malignancies. The author Edgar Overton said there is a suggestion that greater significant benefit may be found in certain sub-groups of patients such as older patients over 50 or 60, but further studies would have to be performed to examine these questions & confirm if & how statin therapy might reduce the risk of developing non-AIDS complications & related deaths.
Here is link to webcast of session on wednesday where this study was presented as one of several oral presentations in the session called: "Metabolic and Cardiovascular Complications"
http://app2.capitalreach.com/esp1204/servlet/tc?c=10164&cn=retro&s=20481&&dp=player.jsp&e=16637&mediaType=podiumVideo
Slides provided by author Edgar Overton
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