| |
HIV Reduced Survival and Comorbidities
|
| |
| |
from Jules: for an HIV+ person with several comorbidities - bone disease, heart disease, kidney disease, cancer, diabetes,neuropathy, frailty, cognitive impairment - how more do you think survival is reduced??? and what about quality of life? how much worse is quality of life for older aging HIV+ who have several serious comorbidities including frailty? Hello ! much worse. SO how much recognition & attention is this getting ????? Not ENOUGH. AND what about depression, isolation,mobility & gait problems, housing & income problems - how much do you think this will reduce survival???? HELLO AGAIN ! A LOT !! Multi-comorbidity & polypharmacy are he norm among older aging HIV+. On average older HIV+ have 3-6 comorbidities & are taking 6-14 comedications, these alone increase risk for frailty and drug toxicity, andadherence fatigue and depression.
Long-Term Mortality in HIV-Infected Individuals 50 Years or Older: A Nationwide, Population-Based Cohort Study - (02/08/16)
We detected a 1.6-fold increased risk of death of among HIV-infected individuals ≥ 50 years without comorbidity compared with population controls without comorbidity, which is in line with the findings of Lohse et al who found a 1.7-fold increased mortality in HIV-infected individuals with CCI = 0 compared with population controls with CCI = 0.
"Among HIV-infected individuals without comorbidity the estimated median survival time from age 50 years was 25.6 years (to age 75.6 years) (95% CI: 23.8 to NA) compared with 34.2 years (age 84.2 years) (95% CI: 29.6 to 38.3) among population controls without comorbidity. MRR was 1.7 (95% CI: 1.2 to 2.3) for HIV-infected individuals compared with population controls.
|
|
| |
| |
|
|
|
