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If you don't clear the virus in the first 12 weeks you probably won't have a sustained response?
 
 
Dear Dr. Chung,
 
 
 
I have been on peg combo treatment for 12 weeks. My viral load went from 1 million to 79,000. My Dr was hoping for better. I read that if u don't clear the virus in the first 12 weeks you probably won't have a sustained response. your opinion? Also I found a website that describes the profile for non-responders. 1. over 45 2. Genotyoe 1 3. had HVC over 5 years 4. high viral load 5. Liver scarring I fit the first 3 and 4 if u consider 1 million high viral load. I am stage 2. I don't want stay on this TX if I don't fit the profile to respond your opinion.
 
 
 
 
 
 
  Dr Chung Writes-  
 
 
Probably true, although the 12 week rule was developed for PEGasys combo, not PEGINTRON combo. those criteria for nonresponders are not hard and fast. if you are genotype 1 and are having a bumpy time with therapy, you may wish to consider stopping early, and waiting for better and better tolerated therapies down the road.
 
 
  Dr. Chung      
 
 
 
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