icon-    folder.gif   Conference Reports for NATAP  
  20th Conference on Retroviruses and
Opportunistic Infections
Atlanta, GA March 3 - 6, 2013
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Trends in and factors associated with virological failure among women conceiving on cART in Western Europe
  Reported by Jules Levin
CROI 2013
H Bailey, C L Townsend, M Cortina-Borja and C Thorne for the European
Collaborative Study in EuroCoord
UCL Institute of Child Health, University College London


- 19% (74/396) of women had virological failure, with a median viral load of 1370 copies/ml (IQR 480, 6000).
- The proportion with virological failure declined ten-fold from 34% (32/93) in 2000-01 to 3% (1/33) in 2010-11 (trend p<0.01, Figure 1); 64 of the 74 women with virological failure enrolled prior to 2006.
- Median age 33 yrs; 56% from sub-saharan Africa, 33% had CD4 <350
- 37% of women were on a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimen (mostly nevirapine);