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Integrated HIV DNA and Associated Histiocyte Marker mRNA in Autopsy Samples of Non-lymphoid Tissue Including the CNS
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Reported by Jules Levin
CROI 2013
Benjamin B. Gelman1,3, Tiansheng Chen1, Joshua G. Lisinicchia1, Dennis L. Kolson2, Andrew P. Rice3
1University of Texas Medical Branch, Galveston, TX, 2University of Pennsylvania, Philadelphia, PA, 3Baylor College of Medicine Center for AIDS Research, Houston, TX
CROI: The Kidney at CROI 2013 - Christina M. Wyatt, MD Assistant Professor, Medicine/ Nephrology Mount Sinai School of Medicine New York, NY - (03/21/13)
"In an autopsy study of 5 HIV-infected individuals (abstract 373), integrated HIV DNA was found in kidney and brain tissue, supporting a hypothesized role of local HIV infection in the pathogenesis of both neurocognitive impairment and CKD, and providing further evidence that these non-lymphoid tissues may serve as latent HIV reservoirs."
webcast themed session
http://webcasts.retroconference.org/console/player/19416?mediaType=podiumVideo
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