icon-    folder.gif   Conference Reports for NATAP  
  22nd Conference on Retroviruses and
Opportunistic Infections
Seattle Washington Feb 23 - 26, 2015
Back grey_arrow_rt.gif
Incidence and Risk of Myocardial Infarction
(MI) by Type in the NA-ACCORD
  "Traditional CVD risk factors (older age, cigarette smoking, HTN, DM, low HDL cholesterol, stage 4---5 CKD, and statin use) were significantly associated with higher risk of primary MI (Table 2)......After controlling for traditional CVD risk factors, HIV---related factors were independently associated with increased risk of primary MI (Table 2)"
from Jules: CD4 <500 was a risk factor for a primary MI, in particular the lower the CD4 the greater the risk, viral load over 400 increased risk 56% & a history of clinical AIDS increased risk 26%...the authors concluded: managing HIV-related risk factors (CD4/viral load) for MI including optimizing ART-mdiated viral suppression to prevent progression to lower CD4 nadir & clinical AIDS, as well as to maximize CD4 immune reconstitution (another pout for early ART start..... .....look at Figure 3, you will see risk for primary MI more than doubles after age 60 & risk for secondary MI goes up about 50% after age 60......history of injection drug use increased risk 29%
Reported by Jules Levin
CROI 2015 Feb 23-26, Seattle, WA
Daniel Drozd1, Mari Kitahata1, Susan Heckbert1, Heidi Crane1, Keri Althoff2, Jinbing Zhang2, Matthew Budoff3, Frank Palella4, Daniel Klein5, Richard Moore6 1 University of Washington, Seattle, Washington, United States;2 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States;3 Division of Cardiology, University of California Los Angeles, Los Angeles, California, United States;4 Division of Infectious Diseases, Northwestern University, Chicago, Illinois, United States;5 Division of Infectious Diseases, Kaiser Permanente Northern California, Hayward, California, United States;6 Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States