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Lipoprotein(a) Testing Guidelines, at Cleveland Clinic
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The experience of the Cleveland Clinic serves as a model for the kind of critical data that universal testing provides. 4 For over 10 years, every patient enrolled in the cardiac prevention program had an Lp(a) test. Follow-up of this 25,000-plus patient base has confirmed the increased incidence of coronary and cerebrovascular events as well as an increased incidence of CAS and a striking acceleration to severe valvular obstruction in those with elevated Lp(a) levels. A substantial, unequivocal increase in mortality associated with this powerful risk factor was identified from this dataset. These findings support that early identification of individuals with high Lp(a) levels should not only prompt aggressive risk factor intervention, but also vigilance for early onset of peripheral, coronary, carotid, and aortic valvular disease.
https://www.thecardiologyadvisor.com/home/topics/metabolic/lipoprotein-a-testing-guidelines-atherosclerotic-cardiovascular-disease-ascvd-cas/
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