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Health-related quality of life in ageing people with HIV is not different to that of
well-matched controls without HIV: an 8-year longitudinal analysis from the AGEhIV cohort study on ageing and comorbidities
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from Jules: of note this was a highly well educated group; PWH were only at most 60 yrs old; mostly dutch white MSM, half were physically active, most had only 0 or 1 comorbidity, 41% college degree or higher, so a very select group. So, this study population is much different than the ovrrall USA HIV populatipn. Plus, as the authors say the QOL test they used SF-36 may not adequately capture the real experiences of PWH, but the authors suggest perhaps these PWH "adapt" to their changing circumstances and that might reflect not too bad of a QOL, perhaps I would say they are in denial or unaware of their real conditions. BUT, in the USA many older PWH clearly are aware of a worse QOL blog with many physical & mental comorbidities.
response to my inquiry to authors about these unexpected results:
Yes, you're right, AGEhIV has consistently shown that people with HIV have more comorbidities than controls. This study looked at changes over time and we were surprised to find that the difference between the two groups - which was minor according to the SF-36 - remained stable over time. Perhaps people with HIV adapt en maintain resilience to deterioration in their quality of life over time.
We also looked at depressive symptoms specifically and found that there was a higher probability for people with HIV.
The way we interpret this is that perhaps population-based generic quality of life measures do not capture granular aspects of quality of life that affect people with HIV and that it's important to also screen for specific conditions - such as depression - to identify specific issues in individuals that could affect their quality of life.
Therefore, while we should continue to measure general quality of life at the population level, we need to advocate for screening of specific conditions at clinic level.
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