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Is coming off semaglutide slowly the key to preventing weight regain?
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May 11, 2024
•Patients who tapered off the drug kept off lost weight for at least 6 months, Danish study finds
•Lower doses of the drug as effective for weight loss as higher ones
Green visual communications (both abstracts)
New research being presented at the European Congress on Obesity (ECO) in Venice, Italy (12-15 May) has explored the benefits of giving personalised doses of semaglutide to patients taking part in a weight loss programme and tapering them off the medication when they reach their target weight. The study is by researchers at Embla, a digital weight loss clinic based in both Copenhagen, Denmark and London, UK, led by Dr Henrik Gudbergsen, the lead researcher and Embla’s Chief Medical Officer.
It found that lower doses were just as effective as higher doses and that slowly reducing medication while focusing on lifestyle changes prevents weight regain.
However, they can cause side-effects such as diarrhoea, nausea, vomiting, dizziness and headaches and many patients quickly regain much of the weight they have lost after they stop taking the medication.
Recent research, however, indicates that patients who receive nutrition and exercise coaching and support tackling issues linked to emotional eating, for example, alongside their weight-loss medication, are less likely to regain weight. Some studies also indicate that coming off the medication slowly may help prevent weight regain.
https://easo.org/is-coming-off-semaglutide-slowly-the-key-to-preventing-weight-regain/
Weight Loss Maintained With Slow Taper of Semaglutide
May 14, 2024
VENICE, ITALY - Personalized doses and slow tapering of semaglutide (Wegovy or Ozempic, Novo Nordisk) in patients who also follow a digital weight loss program can lead to maintenance of target weight up to 6 months later, show retrospective, real-world data.
Lower doses were found to be just as effective as higher doses for weight loss. Slowly reducing medication while focusing on lifestyle changes using a digital program seemed to help prevent weight regain, said the study lead Henrik Gudbergsen, MD, lead researcher and chief medical officer at Embla, a digital weight loss clinic, in Copenhagen, Denmark.
https://www.medscape.com/viewarticle/weight-loss-maintained-slow-taper-semaglutide-2024a100095i
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