30 Years of Viral Suppression: A Biologic Reset? HIV Reservoir: Persistence and Expansion Under Long-Term ART

Conference Reports for NATAP

Conference on Retroviruses
and Opportunistic Infections
Denver, CO 80202, United States
February 22 - 25, 2026


30 Years of Viral Suppression: A Biologic Reset? HIV Reservoir: Persistence and Expansion Under Long-Term ART

	CROI 2026 John W. Mellors University of Pittsburgh, Pittsburgh, PA, USA webcast: https://www.croiwebcasts.org/console/player/55147 A Few Selected CROI “Cure”, Viral Control Highlights Altered Viral Kinetics at ATI After Dual LS-bNAbs Plus ART: A Preliminary Analysis of RIO Arm B - (03/05/26) Refractory HIV-Expressing CD4+ T Cells Retain Infectivity After NNRTI-Induced CARD8 Activation - (03/10/26) Bispecific Biologics That Target and Activate the HIV Latent Reservoir Ex Vivo and In Vivo - (03/10/26) CARD8 Activation for Reservoir Reduction with Efavirenz (CARRE Trial) An open-label, single arm trial to assess the safety and efficacy of in vivo CARD8 activation with Efavirenz intensification on HIV-1 reservoir reduction in people living with HIV-1 - (03/07/26) AUTOLOGOUS NEUTRALISING ANTIBODIES AND EFFECTIVE CD8 T-CELLS MAINTAIN HIV POST-INTERVENTION CONTROL - (03/05/26)